Recombinant protein were subjected to SDS PAGE followed by western blot with FNab04358(IFNG antibody) at dilution of 1:800
Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using FNab04358(IFNG Antibody) at dilution of 1:50
Background
Interferon gamma(IFNG) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis(TB). Mutations in this gene are associated with aplastic anemia.